| Epidural anesthesia | regional anesthesia | 1921 | Fidel Pages | Spain
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| Band aid | sterile adhesive bandage | 1921 | Earle Dickson | USA
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| Polygraph | lie detector test | 1921 | John Augustus Larson | USA
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| Q tips | cotton tipped swabs | 1923 | Leo Gerstenzang | USA
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| Electroencephalogram | EEG test, brain electrical activity | 1924 | Hans Berger | Germany
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| Carpal tunnel release surgery | treatment for hand numbness and pain | 1924 | Herbert Galloway | Canada
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| Tetanus toxoid vaccine | prevents lock jaw infection | 1925 | Alexander Thomas Glenny et al. | UK
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| Pertussis vaccine | prevents whooping cough | 1926 | Leila Denmark | USA
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| Diphtheria toxoid vaccine | prevents diphtheria | 1927 | Alexander Thomas Glenny et al. | UK
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| Iron lung respirator | breathing machine | 1927 | Phillip Drinker,Louis Agassiz Shaw | USA
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| Penicillin | blockbuster antibiotic | 1928 | Alexander Fleming | UK (19)
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| Cardiac pacemaker | wired heart rhythm correction | 1928 | Mark Lidwell | Australia
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| Cotton tampon | menstruation management | 1930 | Earle Cleveland Haas | USA
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| Breathalyzer | blood alcohol assessment | 1931 | Rolla Neil Harger, Indiana U. | USA
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| Hydrocortisone | potent anti-inflammatory medication | 1936 | Percy Lavon Julian | USA
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| Blood bank | transfusion management | 1937 | Charles Richard Drew, Bernard Fantus, Chicago | USA
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| Hip replacement surgery | fractures, arthritis | 1940 | Austin Moore | USA
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| Hemodialysis | replaces kidney function | 1943 | Willem J. Kolff | Netherlands
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| Lidocaine, Xylocaine | local anesthesia | 1943 | Nils Lofgren | Sweden
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| Chemotherapy for cancer | nitrogen mustard | 1946 | Alfred Gilman, Louis S. Goodman | USA
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| Methotrexate immunosupression | treat inflammation | 1947 | Sidney Farber | USA
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| Acetaminophen (Tylenol) | pain reliever, antipyretic | 1948 | Julius Axelrod, Bernard Brodie | USA
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| Electrolyte replacement for diarrhea | oral and intravenous fluids | 1949 | Daniel C. Darrow, Harold Harrison | USA
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| Succinylcholine | muscle relaxant for anesthesia paralysis | 1949 | Daniel Bovet | Italy
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| Artificial intraocular lens | lens replacement for cataracts | 1949 | Harold Ridley | UK
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| Holter monitor | detects abnormal heart rhythms | 1949 | Norman Jeffferis Holter | USA
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| Nystatin, Mycostatin | antifungal medicine | 1950 | Rachel Fuller Brown, Elizabeth Lee Hazen | USA
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| Thorazine, chlorpromazine | psychotrophic medicine | 1951 | Heni Laborit, Pierre Deniker, Heinz Lehmann | France/Canada (87)
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| Salk polio vaccine | polio prevention | 1952 | Jonas Salk | USA
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| Apgar score | newborn health assessment | 1952 | Virginia Apgar | USA
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| Isoniazid for tuberculosis | second biggest killer in history | 1952 | Meyer and Malley | Czechoslovakia
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| Heart lung machine | allows for heart surgery on a stopped heart | 1953 | John Heysham Gibbon | USA
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| Vancomycin antibiotic | treats severe staph and strep infections | 1953 | Edmund Kornfeld | USA
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| Cochlear implant | hearing surgery | 1953 | Andre Djourno | France
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| Catheter surgery | minimally invasive surgery, Seldinger technique | 1953 | Sven Ivar Seldinger | Sweden (79)
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| Ultrasound, echocardiogram | sound waves for diagnosis | 1953, 1956 | Inge Edler, Carl Hertz, Ian Donald, Tom Browen | Sweden /UK (75)
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| Prednisone | cortisone pill anti-inflammatory | 1954 | Arthur Noble | UK
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| Kidney transplant | most common organ transplant | 1954 | Joseph E. Murray | USA
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| Cardiopulmonary resuscitation | CPR | 1954 | Peter Safar, James Elam | USA
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| Chlorhexidine | topical skin disinfectant | 1954 | Imperial Chemical Industries, Ld. | UK
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| Betadine, povodine-iodine | topical skin disinfectant | 1955 | H.A. Shelanski, M.V. Shelanski | USA
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| Metered dose inhaler | asthma/COPD therapy | 1956 | Charlie Thiel, 3M | USA
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| Bone marrow transplant | blood cancer therapy | 1956 | E. Donnall Thomas | USA
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| Birth control pill | sexual freedom, contraception | 1956, 1960 | Gregory Pincus, John Rock, Min Chueh Chang | USA (100)
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| Endoscopy, fiberoptic flexible | upper and lower gastrointestinal | 1957 | Basil Hirschowitz, Larry Curtis, Wilbur Peters | USA
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| Haloperidol, Haldol | antipsychotic, schizophrenia | 1958 | Paul Janssen | Belgium
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| Lasix, furosemide diuretic | for swelling, edema, fluid retention | 1959 | Sanofi | USA
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| Valium, diazepam sedative | for anxiety | 1959 | Leo Sternbach | USA
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| DOPA for Parkinson's disease | anti-tremor effects | 1960 | Oleh Hornykiewicz | Austria
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| Coronary artery bypass graft, heart | CABG | 1960 | Robert Goetz, Michael DeBakey | USA
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| Ibuprofen, Motrin, Advil | non-steroidal anti-inflammatory medicine | 1960 | Stewart Adams | UK
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| Liver and lung transplants | organ transplants | 1963 | Thomas Starzl, James Hardy | USA
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| Portable heart defibrillator | advanced CPR | 1965 | Frank Pantridge | UK
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| Commercial ultrasound | obstetrics | 1965 | Walter Erich Krause | USA
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| Rubella vaccine | prevents German measles | 1965 | Harry Martin Meyer, Paul Parkman | USA
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| Oral Sabin vaccine | prevents polio with no injection needed | 1966 | Albert Bruce Sabin | USA
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| Heart transplant | successful | 1967 | Christiaan Neethling Barnard | South Africa
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| Fogarty balloon catheter | removes clots, minimally invasive | 1969 | Thomas Fogarty | USA
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| Digital thermometer | more accurate temperatures | 1970 | Robert Cherry Martin | USA
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| Transdermal patch | drug delivery through the skin | 1971 | Alejandro Zaffaroni | USA
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| Pulse oximeter | measures blood oxygen level | 1972 | Takuo Aoyagi | Japan
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| Computed tomography scan | CT scan | 1972 | Godfrey Hounsfield, Allan Cormack, Robert S. Ledley | UK/USA
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| Magnetic resonance imaging | MRI scan, no radiation | 1973 | Raymond Damadian, Paul Lauterbur | USA (74)
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| Prozac | antidepressant medication | 1972 | Ray W. Fuller, Bryan B. Molloy, David T. Wong | USA
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| LASER eye surgery, Lasik | vision correction with surgery | 1973 | Mani Lal Bhaumik | India/USA
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| Liposuction | cosmetic surgery | 1974 | Giorgio Fischer | Italy
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| Total knee replacement surgery | cemented metal and plastic parts | 1974 | John Insall | USA
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| Heimlich maneuver | food bolus extraction | 1974 | Henry Judah Heimlich | USA
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| Versed, midazelam | conscious sedation IV | 1975 | Armin Walser | Switzerland
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| Positron emission tomography | PET scan, cancer assessment | 1977 | Edward J. Hoffman, UCLA | USA
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| In vitro fertilization | test tube baby | 1978 | Patrick Steptoe, Robert Edwards | UK
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| Lithotrypter for gallstones | focused sound to break down gallstones | 1980 | Claude Dornier | Germany
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| Hepatitis B test and vaccine | diagnosis and prevents hepatitis B | 1980 | Baruch Samuel Blumberg | USA
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| Mumps vaccine | prevents mumps | 1981 | Maurice Hilleman | USA
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| Artificial heart | Jarvik -7 | 1982 | Paul Winchell, Willem Johan Kolff, Robert Jarvik | USA
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| Humulin | recombinant insulin | 1982 | Genentech | USA
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| RU-486 abortion pill | avoids surgery | 1988 | Etienne-Emile Baulieu | France
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| Intravascular stent | catheter placed stent in obstructed blood vessel | 1988 | Julio Palmaz | Argentina
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